20th February 2024

A 40-year-old gentleman presents to the neurology clinic with involuntary movements of his hands

A 40-year-old gentleman presents to the neurology clinic with involuntary movements of his hands and legs. His wife notes that he has been experiencing odd, jerky movements of his hands and legs at unpredictable times. He has also been more careless and has been found dropping things around the house. His wife also notes that he has had a shorter temper than usual over the past three months. He denies any overt hallucinations. He has not taken any new medications.

Given the likely diagnosis, what is the likely underlying genetic mutation?

Select the SINGLE most appropriate option from the list below. Select ONE option only.