A 42-year-old female has an endocrinology appointment after being referred by her GP. She originally presented with a 12 month history of drowsiness | Medibuddy
16th September 2024

A 42-year-old female has an endocrinology appointment after being referred by her GP. She originally presented with a 12 month history of drowsiness

A 42-year-old female has an endocrinology appointment after being referred by her GP. She originally presented with a 12 month history of drowsiness, weight loss and excessive thirst. Six months ago, her GP did an HbA1c test, which came back as 50 mmol/mol. She was started on metformin and her symptoms improved slightly but are still present. She exercises once a week and eats a relatively balanced diet, but one high in fat. Her BMI is 30. The endocrinologist performs several tests which are shown below:

C peptide 0.4ng/ml (0.5 to 2.0)
Serum ketones 0.4 mmol/l (<0.6 mmol/l)
HbA1c 48mmol/mol (<48)
Autoantibodies Positive for anti-GAD antibodies

Which of the following is the most likely diagnosis given the above?

Select the SINGLE most appropriate option from the list below. Select ONE option only.

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