31st July 2023

A 42-year-old gentleman presents to his GP with rectal bleeding, abdominal pain and a new onset of diarrhoea

A 42-year-old gentleman presents to his GP with rectal bleeding, abdominal pain and a new onset of diarrhoea. His bloods show a microcytic anaemia and low ferritin, and he is referred to gastroenterology under a two-week wait pathway. On colonoscopy, he is found to have a colorectal adenocarcinoma.

Which of the following genetic conditions is LEAST associated with an increased risk of colorectal cancer?

Select the SINGLE most appropriate option from the list below. Select ONE option only.