1st August 2023

A 42-year-old man with pharyngeal cancer is seen in an outpatient clinic a week prior to starting his next cycle of chemo-radiotherapy.

A 42-year-old man with pharyngeal cancer is seen in an outpatient clinic a week prior to starting his next cycle of chemo-radiotherapy. He is on his second day of a course of nystatin for oral thrush and complains of new pain and difficulty swallowing, although he can still tolerate small amounts of food. On examination, he has noticeably bad breath, and his tongue and oral cavity are extensively coated in creamy-white plaques.

What is the most appropriate treatment option?

Select the SINGLE most appropriate option from the list below. Select ONE option only.