1st July 2023

A 42-year-old woman presents with a solitary, well-defined, hyperpigmented lesion on the dorsal aspect of her left hand

A 42-year-old woman presents with a solitary, well-defined, hyperpigmented lesion on the dorsal aspect of her left hand. She tells you that the lesion develops within an hour of taking Ibuprofen, which later resolves, leaving a dark patch. This happens in the same location every time she takes Ibuprofen. Other than taking regular Ibuprofen for chronic muscle aches and pains, she is systemically well. On examination, the lesion is tender to touch.

What is the most likely diagnosis?

Select the SINGLE most appropriate option from the list below. Select ONE option only.