18th February 2024

A 43-year-old male from Namibia presents to the acute medical unit with weight loss

A 43-year-old male from Namibia presents to the acute medical unit with weight loss and night sweats. He states that he has a chronic cough with occasional haemoptysis. Chest X-ray reveals a calcific body within the right upper lobe with associated mediastinal lymphadenopathy. Gamma QuantiFERON test is positive.

Given the likely diagnosis, which of the following best describes the pathophysiology of the lung lesion?

Select the SINGLE most appropriate option from the list below. Select ONE option only.