26th June 2023

A 44-year-old male with a history of hepatitis C presents with frothy urine, periorbital oedema, joint pain, and generalised weakness.

A 44-year-old male with a history of hepatitis C presents with frothy urine, periorbital oedema, joint pain, and generalised weakness. On examination, he has palpable purpura on his lower limbs and reduced sensation in his toes.

Which cells are responsible for the splitting of the glomerular basement membrane in this type of nephropathy?

Select the SINGLE most appropriate option from the list below. Select ONE option only.