A 45-year-old female presents to her GP with generalised fatigue and malaise
A 45-year-old female presents to her GP with generalised fatigue and malaise. She does not note any other symptoms and does not have any abdominal pain. She does not recall any bleeding issues or increased menstrual flow. She does not have any mental health issues. She does not drink any alcohol and has a BMI of 16. She denies any past medical history and notes that both her parents are well without any history of liver disease.
Examination of her abdomen is unremarkable. Blood tests were performed and are as follows:
| Blood test | Value | Normal range |
|---|---|---|
| Haemoglobin | 130g/L | 120-150g/L |
| Bilirubin | 16 | <21μmol/L |
| ALT | 90U/L | <41U/L |
| AST | 100U/L | 1-45U/L |
| ALP | 160 U/L | 30-130U/L |
| Ferritin | 850ng/ml | <300ng/ml |
| Transferrin saturation | 75% | 20-50% |
| CRP | <5mg/L | <5mg/L |
The remainder of her liver screen is unremarkable, with a normal autoantibody screen.
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