13th March 2024

A 45-year-old woman presents to her GP following a syncopal episode a few days earlier.

A 45-year-old woman presents to her GP following a syncopal episode a few days earlier. She denies chest pain or vertigo but does report feeling light-headed and short of breath on minimal activity. She has also lost around 4 kg of weight in two months. She has no other medical issues, takes no regular medications, and there are no peripheral stigmata of disease. On examination the patient is afebrile, has a raised JVP and a blood pressure of 144/80 mmHg. On auscultation there is a loud first heart sound. Neurological examination is unremarkable. Which of the following options is the most likely diagnosis? 

Select the SINGLE most appropriate option from the list below. Select ONE option only.