27th May 2023

A 50-year-old female presents to the emergency department in severe septic shock

A 50-year-old female presents to the emergency department in severe septic shock, with an unclear source of infection. She has widespread purpura and urgent bloods demonstrate raised APTT, PTT, and low fibrinogen. Hb is 85g/L and platelets are 60 x 10⁹. A diagnosis of disseminated intravascular coagulation secondary to sepsis is made.

What is the most appropriate blood product to give to correct the deranged coagulation?