24th July 2023

A 50-year-old woman with a known history of hepatitis B presents to her GP surgery with fatigue

A 50-year-old woman with a known history of hepatitis B presents to her GP surgery with fatigue, weight loss, fever, and arthralgia. She has also noticed several lesions across her body, which are variably purpuric or tender and erythematous. Neurological examination demonstrates an asymmetric polyneuropathy, with marked motor and sensory deficit in the radial and ulnar nerve.

Given these findings, what is the most likely diagnosis?

Select the SINGLE most appropriate option from the list below. Select ONE option only.