16th February 2024

A 54-year-old female presents with recurrent facial swelling

A 54-year-old female presents with recurrent facial swelling. She also reports multiple episodes of urticaria without a clear trigger. Her father had similar symptoms and passed away after severe laryngeoedema, resulting in respiratory arrest. She had trialled antihistamines and steroids without any improvement. Blood tests were normal, with normal serum tryptase levels. Eosinophil levels were normal. Complement levels revealed normal C3 levels with low C4 levels. C1-INH levels were undetectable.

Given the likely diagnosis, which of the following treatments provides definitive treatment during an anaphylaxis episode?

Select the SINGLE most appropriate option from the list below. Select ONE option only.