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17th September 2024
A 56-year-old female presents to the endocrine clinic with weight gain despite having a normal appetite
A 56-year-old female presents to the endocrine clinic with weight gain despite having a normal appetite and no significant family history. She consumes 4 units of alcohol per week, does not report any particular social stress and takes no regular medication. On examination, she has an increased BMI, central adiposity, purple striae on her abdomen and an increased fat pad between her shoulder blades.
| 24 hour urine cortisol | 268 nmol (<146) |
| Low dose dexamethasone suppression test (48-hour cortisol level measured) |
380 nmol /l (<50) |
| High dose dexamethasone suppression test | ACTH high
Cortisol high |
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Select the SINGLE most appropriate option from the list below. Select ONE option only.
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