26th June 2023

A 57-year-old male is admitted to A&E with arthralgia and a rash and is treated for likely acute interstitial nephritis.

A 57-year-old male is admitted to A&E with arthralgia and a rash and is treated for likely acute interstitial nephritis. He started treatment for Burkitt’s lymphoma with rituximab plus cyclophosphamide, vincristine, doxorubicin and methotrexate, and the oncologist also started him on lots of medications to prevent the common side effects, but the patient can’t remember them all.

Which medication is likely to be responsible for the patient developing acute interstitial nephritis?

Select the SINGLE most appropriate option from the list below. Select ONE option only.