23rd July 2023

A 57-year-old man presents to his GP, after his husband has commented that his skin looks yellow

A 57-year-old man presents to his GP, after his husband has commented that his skin looks yellow. He admits he has been feeling very lethargic. He has a past medical history of type 2 diabetes mellitus and atrial fibrillation. Drug history includes metformin, linagliptin, and amiodarone. He is a non-smoker and does not drink any alcohol. He tries to maintain a healthy lifestyle and has a BMI of 21. With regards to family history, he tells you his father died from liver disease many years ago, but he is unsure what type of liver disease he had.

On examination, he has jaundiced sclera, and in general, he appears tanned, but his face has a grey colour.

What is the most likely diagnosis?

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