A 64 year old retired accountant is diagnosed with HFrEF after presenting with progressive shortness of breath on exertion and orthopnoea.
A 64 year old retired accountant is diagnosed with HFrEF after presenting with progressive shortness of breath on exertion and orthopnoea. He is started on medications, including dapagliflozin, eplerenone, bisoprolol and sacubitril/valsartan. What is the mode of action for sacubitril?
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