19th February 2024

A 65-year-old male presented to the acute medical unit with a 1-month history of progressive unsteadiness

A 65-year-old male presented to the acute medical unit with a 1-month history of progressive unsteadiness. He mobilises with a broad-based gait. His wife noted slurred speech. He noticed tingling and numbness along his hands and feet. Examination revealed loss of all sensory modalities in his upper and lower limbs. Romberg’s test was positive. Normal power in all four limbs. CXR revealed a 2cm irregular mass within the right upper lobe, and a paraneoplastic syndrome is suspected.

Which of the following autoantibodies is likely associated with this condition?

Select the SINGLE most appropriate option from the list below. Select ONE option only.