20th February 2024

A 67-year-old male has presented to the haematology clinic with an incidentally raised white cell count (WCC) of 30

A 67-year-old male has presented to the haematology clinic with an incidentally raised white cell count (WCC) of 30. He has no symptoms suggesting infection, and his examination is normal. Peripheral blood smear confirms the presence of mature myeloid cells, with PCR testing confirming the presence of the BCR-ABL fusion gene within the bone marrow.

Which of the following chromosomal abnormalities has led to the condition?

Select the SINGLE most appropriate option from the list below. Select ONE option only.