18th February 2024

A 68-year-old female presents to the acute medical unit with jaundice and dark urine

A 68-year-old female presents to the acute medical unit with jaundice and dark urine. This has insidiously come on over the past three months. She denies any weight loss. She denies any episodes where her extremities turned blue. Blood tests show significant anaemia with Hb of 40g/L with normal WBC and platelet counts. LFTs show an isolated unconjugated hyperbilirubinemia. She has increased reticulocytes, LDH and haptoglobins. The Coombs test was positive.

Which of the following is the likely diagnosis?

Select the SINGLE most appropriate option from the list below. Select ONE option only.