A 70-year-old female presents to her GP with intermittent pruritus
A 70-year-old female presents to her GP with intermittent pruritus. In particular, this affects her fingers and toes and is associated with a burning sensation and red discolouration. Her blood results are shown below:
| Hb | 180 g/L | (120-170 g/L) |
| WCC | 12.5 x 10⁹/L | (3.6-11 x 10⁹/L) |
| Platelets | 460 x 10⁹/L | (150-400 x 10⁹/L) |
| HCT | 0.62 | (0.36-0.48) |
| EPO | 0.6 mIU/ml | (2.6-15.8 mIU/ml) |
| Bilirubin | 16 µmol/L | (<21 µmol/L) |
Which genetic aberration is most likely to be responsible for this?
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