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1st June 2023
An 18-year-old woman is reviewed in the Haematology clinic
An 18-year-old woman is reviewed in the Haematology clinic. She recently attended the dentist for a tooth extraction and suffered prolonged bleeding following the procedure. She mentions that her father suffers from a bleeding disorder and takes medication prior to any operative procedures, but she is unsure what the name of this medication is. She complains of longstanding menorrhagia since starting her periods but is otherwise well with no past medical history. Physical examination is unremarkable.
Bloods taken prior to the clinic appointment show:
| Hb | 123 g/l | Females: (115 – 155 g/L) |
| Platelets | 324 x 10⁹/L | (150 – 400 x 10⁹/L) |
| WCC | 7.8 x 10⁹/L | (4 – 11 x 10⁹/L) |
| Na+ | 141 mmol/L | (135 – 145 mmol/L) |
| K+ | 4.2 mmol/L | (3.5 – 5.0 mmol/L) |
| Urea | 3.2 mmol/L | (2.5 – 6.5 mmol/L) |
| Creatinine | 45 μmol/L | (50 – 120 μmol/L) |
| CRP | 5 mg/L | (0 – 10 mg/L) |
| PT | 12s | (10.6 – 14.9s) |
| APTT | 25s | (23.0 – 35.0s) |
What is the likely diagnosis?
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