19th February 2024

An 80-year-old female presents to the acute medical unit with a generalised headache

An 80-year-old female presents to the acute medical unit with a generalised headache. This has acutely worsened in the past 48 hours. She described several episodes of vision loss in her left eye, which had spontaneously resolved. She had joint and muscle pains that worsened over this period and were initially considered age-related. Palpation of her temples revealed thickened and tender temporal arteries. Blood tests revealed significantly elevated ESR levels.

Given the likely diagnosis in this case, which of the following hypersensitivity reactions is responsible for this condition’s pathogenesis?

Select the SINGLE most appropriate option from the list below. Select ONE option only.