2nd August 2023

An 83 year old lady presents with a 5 day history of fever and lethargy. She has a history of advanced Alzheimer’s disease

An 83 year old lady presents with a 5 day history of fever and lethargy. She has a history of advanced Alzheimer’s disease and is on memantine and quetiapine. She lives in an unkempt house with multiple cats, and her carers have often seen her making sandwiches out of cat litter. You send serology for toxoplasmosis, which comes back positive. There is no evidence of any systemic illness.

What is the first line treatment for the condition?

Select the SINGLE most appropriate option from the list below. Select ONE option only.