20th July 2023

An 86-year-old man is diagnosed with moderate Alzheimer’s disease. He has a past medical history of hypertension

An 86-year-old man is diagnosed with moderate Alzheimer’s disease. He has a past medical history of hypertension, and chronic kidney disease stage 4. He is a current smoker. He has enquired about treatment options.

His baseline assessment is as follows:

• Respiratory rate 15
• SpO2 94% on room air
• Heart rate 48 bpm
• Blood pressure 117/87
• Temperature 36.6°C
• ECG: sinus rhythm, normal axis, PR interval 250ms, QRS 115ms, QTc 400ms

Which of the following is a relative contraindication to starting an acetylcholinesterase inhibitor?

Select the SINGLE most appropriate option from the list below. Select ONE option only.