27th June 2023

Graham is a 60-year-old man who has a background of treated HIV infection, smoking and hypercholesterolaemia.

Graham is a 60-year-old man who has a background of treated HIV infection, smoking and hypercholesterolaemia. He has previously experienced AIDS, but at present his CD4+ T-cell count is greater than 200/μL. He has recently found that he has been more forgetful and that he has been ‘slower’ than usual lately. He is otherwise happy and still enjoys being part of his village cricket team. CT and MRI imaging of the brain is normal. Which of the following is the most likely diagnosis?

Select the SINGLE most appropriate option from the list below. Select ONE option only.