Close
11th April 2024
You review a 15-year-old female who has been referred with primary amenorrhoea.
You review a 15-year-old female who has been referred with primary amenorrhoea. She explains over the last few months, she has had muscle cramps and that her fingertips have been tingling. Her past medical history includes Addison’s disease and chronic mucocutaneous moniliasis. On examination, blood pressure was measured at 105/75, and there were hyperpigmented lesions on the dorsum of the tongue. Bloods reveal the following:
| Hb (135-180 g/L) | 135 |
| WBC (4.0-11.0 * 10^9/L) | 6.2 |
| Platelets (150-400 * 10^9/L) | 350 |
| Na (135-145 mmol/L) | 134 |
| K (3.5 – 5.0 mmol/L) | 4.8 |
| Cr (55-120 umol/L) | 320 |
| Calcium (2.1 – 2.6 mmol/L) | 1.9 |
| Phosphate (0.8 – 1.4 mmol/L) | 1.5 |
| Albumin (34 to 54 g/L) | 48 |
Which of the following is the most likely underlying diagnosis?
Select the SINGLE most appropriate option from the list below. Select ONE option only.
Complete Guide to Clinical Genetics ST3 Application and Recruitment (2027)
Written by Medibuddy. Last updated: October 2026. Clinical Genetics is
Complete Guide to Clinical Radiology ST3 Application and Recruitment (2027)
Recruitment paused: NHS England is not running Clinical Radiology ST3+ recru
Complete Guide to Paediatric Surgery ST3 Application and Recruitment in United Kingdom (2026)
Written by Medibuddy. Last updated: October 2026. If you’re planning
Take your subscriptions with you
Our mobile app allows you to access your interview and exam question banks wherever you are.
