Risk factors
- Early menopause
- Low testosterone in men (i.e. hypogonadism or anti-androgen treatment for prostate cancer)
- Prolonged steroid use (i.e. >5mg/day of prednisolone)
- Alcohol or tobacco use
- Endocrine diseases (i.e. hyperthyroidism, hyperparathyroidism, hypercalciuria & type 1 diabetes)
- Erosive/ inflammatory bone disease (i.e. multiple myeloma or rheumatoid arthritis)
- Dietary (i.e. reduced calcium intake or malabsorptive conditions
- Sedentary lifestyle
- Low BMI (< 18.5)
- Renal or liver failure
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