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9th June 2025
Multiple Endocrine Neoplasia (MEN) 2b
MEN 2b is less common than MEN 2a. Its inheritance pattern is autosomal dominant.
Clinical Features
Unlike MEN 2a, it is associated with Marfan’s syndrome and ganglioneuromas:
- Phaeochromocytoma
- Medullary thyroid cancer
- Marfan’s syndrome
- Neuromas around lips and tongue
- Ganglioneuromas of the bowel
Image Source: Wikimedia Commons (2019). Licensed under a creative commons licence. Available for free at: https://commons.wikimedia.org/wiki/File:Mucosal_Neuromas.png (Accessed 23 May 2025).
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