Management
- There is no licensed drug therapy for PSC (note that ursodeoxycholic acid is not recommended, nor are immunosuppressants such as steroids)
- Cholestyramine for symptomatic relief of pruritus
- Must investigate for underlying colitis with colonoscopy and biopsy (colonic)
- Liver transplant if advanced disease and suitable candidate
- Fat soluble vitamin supplementation
- Screen for osteoporosis
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