24th June 2026

Diagnostic Criteria

The diagnosis of IE is made based on the modified Duke’s criteria, outlined in the table below. A definite diagnosis of IE is defined as the presence of: two major criteria; one major and three minor criteria; or five minor criteria. A possible diagnosis is defined as: one major and one minor criterion or; three minor criteria. These are summarised in table 2:

Table 2: modified Duke criteria for infective endocarditis