11th May 2025

Surgical Management

Patients’ refractory to targeted therapies with severe symptomatic PAH may be considered for transplantation. This includes a single or double lung transplant or a heart-lung transplant. 

In Group 4 patients with CTEPH, pulmonary endarterectomy (PEA) surgery can be performed to remove old blood clots from the lungs. This is recommended alongside life-long anticoagulation and can potentially cure CTEPH with > 90% 5-year-survival.