22nd May 2024

Upper UTI

	First line	Second line
Non-pregnant women and men	Oral – Nitrofurantoin MR 100mg BD for 7 days OR Trimethoprim 200mg BD for 7 days IV – Ceftriaxone 1 to 2g OD or ciprofloxacin 400mg BD/TDS OR Co-amoxiclav 1.2g TDS in culture showing sensitivity	Oral – Pivmecillinam (a penicillin) 400 mg initial dose, then 200 mg three times a day for a total of 7 days IV – consult local microbiologist
In pregnancy	Oral – Cefalexin 500mg BD/TDS for 7 to 10 days IV – cefuroxime 750mg to 1.5g TDS/QDS	Consult local microbiologist
Has upper UTI symptoms	Cefalexin 500 mg BD/TDS for 7 to 10 days OR Co-amoxiclav (only if culture shows susceptibility) 500/125 mg TDS for 7 to 10 days OR Trimethoprim (only if culture shows susceptibility) 200 mg BD for 14 days	Consult local microbiologist

First line

Second line

Non-pregnant women and men

Oral – Nitrofurantoin MR 100mg BD for 7 days OR Trimethoprim 200mg BD for 7 days

IV – Ceftriaxone 1 to 2g OD or ciprofloxacin 400mg BD/TDS

OR Co-amoxiclav 1.2g TDS in culture showing sensitivity

Oral – Pivmecillinam (a penicillin) 400 mg initial dose, then 200 mg three times a day for a total of 7 days

IV – consult local microbiologist

In pregnancy

Oral – Cefalexin 500mg BD/TDS for 7 to 10 days

IV – cefuroxime 750mg to 1.5g TDS/QDS

Consult local microbiologist

Has upper UTI symptoms

Cefalexin 500 mg BD/TDS for 7 to 10 days

OR Co-amoxiclav (only if culture shows susceptibility) 500/125 mg TDS for 7 to 10 days

OR Trimethoprim (only if culture shows susceptibility) 200 mg BD for 14 days

Consult local microbiologist

Complete Guide to Clinical Genetics ST3 Application and Recruitment (2027)

Written by Medibuddy. Last updated: October 2026. Clinical Genetics is

Recruitment paused: NHS England is not running Clinical Radiology ST3+ recru

Written by Medibuddy. Last updated: October 2026. If you’re planning

Our mobile app allows you to access your interview and exam question banks wherever you are.