17th February 2025

A 30-year-old smoker of 15 cigarettes a day presents to his GP with 2 months of worsening shortness of breath and cough.

A 30-year-old smoker of 15 cigarettes a day presents to his GP with 2 months of worsening shortness of breath and cough. On examination, he has a bilateral expiratory wheeze. He has no past medical history of note but has a family history of a brother with liver cirrhosis, which is under investigation.

His lung function tests show the following:

FEV1: 48% of predicted FVC: 80% of predicted

What is the most likely diagnosis? 

Select the SINGLE most appropriate option from the list below. Select ONE option only.