23rd May 2025

A 35-year-old female presents feeling constantly tired and sleepy in the last few months.

A 35-year-old female presents feeling constantly tired and sleepy in the last few months. She noticed her periods have become heavier recently. She has unintentionally gained weight and become increasingly intolerant to cold. On examination, her HR is regular and 65bpm. She has dry cold peripheries. on palpation, her thyroid feels rubbery with symmetrical enlargement. Past medical history is significant for T1DM. Which antibody testing is most likely to be positive with this clinical presentation?

Select the SINGLE most appropriate option from the list below. Select ONE option only.