26th February 2025

A 35-year-old gentleman of Turkish origin presents to the medical take with a swollen, tender right leg.

A 35-year-old gentleman of Turkish origin presents to the medical take with a swollen, tender right leg. On examination, you notice multiple mouth ulcers, and the patient tells you he often suffers with these and that they are painful. He also tells you he has had some painful lumps on his scrotum previously and thought he may have had an STI. You examine with a chaperone present and notice multiple scars on his scrotum consistent with previous ulceration.

US Doppler is performed and shows evidence of deep vein thrombosis in the superficial femoral artery.

Given the likely diagnosis, which is the most likely HLA association?

Select the SINGLE most appropriate option from the list below. Select ONE option only.