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25th July 2024
A 35-year-old male is referred to you following recurrent episodes of mild jaundice that are self limiting
A 35-year-old male is referred to you following recurrent episodes of mild jaundice that are self limiting. He reports they usually are precipitated by viral infections. His past medical history includes a cholecystectomy for recurrent episodes of gallstones and biliary colic but otherwise, he is well and not on any regular medications. He reports that his mum and her father have a blood condition, but they don’t have any treatment for it.
Blood tests show:
| Hb (130 – 180 g/L) | 101 g/L |
| MCHC (32 – 36 g/dL) | 38.5 g/dL |
| Bilirubin (<21 μmol/L) | 37 µmol/L |
| ALT (<41 U/L) | 22 U/L |
| ALP (30–130 U/L) | 64 U/L |
Which investigation would be most likely to reveal the underlying diagnosis?
Select the SINGLE most appropriate option from the list below. Select ONE option only.
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