A 36-year-old female is brought to A&E by her partner with a 24 hour history of headache, fevers, confusion and lethargy
A 36-year-old female is brought to A&E by her partner with a 24 hour history of headache, fevers, confusion and lethargy. On examination, the patient’s GCS is 13 (E3, V4, M6). There is evidence of photophobia and neck stiffness on the neurological exam. Her observations are as follows: HR 108 bpm, BP 92/54 mmHg, RR 20/min, oxygen saturations 99%, temperature 38.1 degrees Celsius.
Blood tests show:
| Hb 141 (115-160) | Neutrophils 8.2 (2-7) | Na+ 134 (135-145) | Urea 3.3 (2-7) |
| WBC 12.1 (4-11) | CRP 34 (<5) | K+ 3.8 (3.5-5) | Creatinine 65 (45-84) |
CT head is normal and lumbar puncture results are pending.
Empirical treatment for meningoencephalitis is started with ceftriaxone, aciclovir and dexamethasone. You discuss the case with the microbiology consultant who recommends adding microbial cover for listeria whilst awaiting the full results. The patient has no known drug allergies.
What medication should you prescribe?
Select the SINGLE most appropriate option from the list below. Select ONE option only.
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