5th June 2025

A 36-year-old patient presents with recent onset of her fingers becoming blue in the cold.

A 36-year-old patient presents with recent onset of her fingers becoming blue in the cold. She has also been struggling with mouth ulcers that keep recurring. Blood tests show mild anaemia and leukopenia, as well as raised CRP and ESR. Further investigations reveal a positive ANA test. She is diagnosed with SLE. 

In an SLE patient with positive anti-dsDNA antibodies, which organ system has a higher chance of being affected?

Select the SINGLE most appropriate option from the list below. Select ONE option only.