A 38-year cold is brought in by ambulance. She is visibly short of breath and delirious | Medibuddy
8th July 2024

A 38-year cold is brought in by ambulance. She is visibly short of breath and delirious

A 38-year cold is brought in by ambulance. She is visibly short of breath and delirious, unable to give a clear history. From the ambulance handover, she had a simultaneous kidney pancreas transplant 4 months ago and is on immunosuppressants. Her brother arrives and tells you she has been unwell with a dry cough and increasing shortness of breath since yesterday. She is on Tacrolimus, MMF, Prednisolone, Aspirin, Ramipril and Atorvastatin. Her vision is poor due to diabetic retinopathy.

Observations and imaging:

Blood Pressure 98/40 mm HG
Heart Rate 118 /min
SpO2 87% on RA, 92% 8lit O2
Temperature 39 ⁰C
Urine analysis 1+Protein
Chest X-Ray Bilateral infiltrates with right sided pleural effusion
ABG on RA pH 7.3, paO2 6.8, paCO2 5.4, HCO3 20, Lactate 2.0
Antigen SARS-CoV2 Negative

Laboratory analysis:

Haemoglobin 10.2 g/dl Sodium 138 mmol/dl
White Blood Corpuscles 8.2 x 10^6 Potassium 5.5 mmol/dl
Platelets 156 x 10^6 Corrected Calcium 2.32 mmol/dl
Creatinine 102 mmol/dl Phosphate 0.9 mmol/dl
Urea 5.6 mmol/dl CRP 123.8 mg/l
Albumin 32 mg/l Glucose 4.0 mmol/dl

What is the most likely cause of this presentation?

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