25th July 2024

A 40-year-old man is brought in by ambulance to A&E following a sudden collapse

A 40-year-old man is brought in by ambulance to A&E following a sudden collapse with loss of consciousness. A CT head identifies an intracerebral haemorrhage. Blood tests show a pancytopenia, elevated D-dimer, low fibrinogen and prolonged prothrombin time. No cerebrovascular abnormalities are identified on CT angiogram. He has no past medical history and no family history of note.

What cytogenetic abnormality might you expect to find on analysis of bone marrow cells?

Select the SINGLE most appropriate option from the list below. Select ONE option only.