19th May 2025

A 42-year-old man has liver function tests performed for routine monitoring after being newly started on an anti-epileptic drug.

A 42-year-old man has liver function tests performed for routine monitoring after being newly started on an anti-epileptic drug. The results are as follows:  

Alanine transferase (ALT): 288 iu/L (3-40 iu/L)

Alkaline phosphatase (ALP): 234 iu/L (30-100 iu/L) 

Aspartate transaminase (AST): 184 iu/L (3-30 iu/L)

Gamma glutamyl transferase (GGT): 97 iu/L (10-60 u/L)

Bilirubin: 57 umol/L (3-20 umol/L)

How can his drug-induced liver injury be classified based on the above tests? 

Select the SINGLE most appropriate option from the list below. Select ONE option only