23rd May 2025

A 43-year-old female was commenced on thyroid hormone replacement after total thyroidectomy for Grave’s disease.

A 43-year-old female was commenced on thyroid hormone replacement after total thyroidectomy for Grave’s disease. She presents with multiple episodes of tonic-clonic seizures for the last 24 hours. A CT head ruled out any bleeding or space occupying lesion. She had EEG which revealed increased electrical activity within the brain. Following neurology specialist review, she is started on carbamazepine for epilepsy management. What should happen with regards to the levothyroxine and carbamazepine doses?

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