5th June 2025

A 50-year-old female has a follow-up appointment with her GP to discuss pain relief options.

A 50-year-old female has a follow-up appointment with her GP to discuss pain relief options. She has a history of fibromyalgia, chronic fatigue, postural tachycardia syndrome and sleep apnoea. On examination, she has hyperelastic skin and some hypermobility features. She was diagnosed with EDS in the past.

Which gene is associated with the second most common subtype of EDS?

Select the SINGLE most appropriate option from the list below. Select ONE option only.