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23rd April 2024
A 50-year-old male with PSC presents with jaundice, weight loss, reduced appetite, and pale stools
A 50-year-old male with PSC presents with jaundice, weight loss, reduced appetite, and pale stools. He does not describe any fevers. On examination, he is thin and icteric.
Investigations show the following:
| Haemoglobin | 115g/L |
| White Cell Count | 10×10⁹/l |
| Platelets | 220 10⁹/l |
| Bilirubin | 180 μmmol/l |
| Alkaline Phosphatase | 400μmmol/l |
| ALT | 55 iu/l |
| AST | 40 iu/l |
| Albumin | 24g/l |
| CRP | 20 mg/l |
| Prothrombin time | 13 seconds |
| Activated Prothrombin Time | 32 seconds |
| INR | 1.3 |
His observations are stable, and he is apyrexial. The abdomen is soft and non-tender.
What would the most appropriate next step be in the management of this patient?
Select the SINGLE most appropriate option from the list below. Select ONE option only.
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