16th February 2025

A 51-year-old lady with chronic obstructive pulmonary disease (COPD) is seen in the respiratory clinic for a routine follow up.

A 51-year-old lady with chronic obstructive pulmonary disease (COPD) is seen in the respiratory clinic for a routine follow up. She is a current smoker with a 60-pack-year smoking history. She complains of a voice change developing over the past year, stating that her voice has deepened in pitch and she now “sounds like a man”. 

What is the most likely diagnosis?

Select the SINGLE most appropriate option from the list below. Select ONE option only.