23rd August 2024

A 57-year-old lady with known breast and ovarian cancer is admitted to hospital with a 2-week history of bizarre behaviour

A 57-year-old lady with known breast and ovarian cancer is admitted to hospital with a 2-week history of bizarre behaviour, confusion and worsening ataxia. A CT head and angiogram is performed, which rules out a stroke or space-occupying lesion. An MRI brain with contrast is performed which shows no abnormality.

You suspect this lady may have paraneoplastic encephalitis. Which antibody may be associated with paraneoplastic encephalitis?

Select the SINGLE most appropriate option from the list below. Select ONE option only.