A 57-year-old male with a past medical history of granulomatosis with polyangiitis
A 57-year-old male with a past medical history of granulomatosis with polyangiitis (10 years ago) is seen in the rheumatology clinic with painless macroscopic haematuria. He was previously prescribed Cyclophosphamide on 3 separate occasions, though he has been well and has not needed any treatment at all in the past 5 years. Other past medical history includes CKD stage 3 and hypertension. Prescribed medications include Ramipril and Amlodipine. On examination, BP is 140/80 and he looks well. Investigations are as follows:
| Haemoglobin | 104 g/L (115-165) |
| White cell count | 13.0 × 10⁹/L (4.0–11.0) |
| Platelets | 302 × 10⁹/L (150-400) |
| Serum sodium | 138 mmol/L (137-144) |
| Serum potassium | 5.7 mmol/L (3.7-4.4) |
| Serum creatinine | 199 µmol/L (60-110) |
| Erythrocyte sedimentation rate | 75 mm/hr (<20) |
| Urinalysis | blood ++ |
Which of the following is the most likely diagnosis?
Select the SINGLE most appropriate option from the list below. Select ONE option only.
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