26th February 2025

A 59-year-old male has been referred to rheumatology with a collection of symptoms that have become progressively worse over the last 4 years.

A 59-year-old male has been referred to rheumatology with a collection of symptoms that have become progressively worse over the last 4 years. He has noted weakness of his grip strength bilaterally and difficulty standing from sitting. He has occasionally noted coughing when eating and drinking recently, which he thinks has become more common. He has no abnormality of speech.

He has no past medical history and takes no regular medications.

As part of his workup, he has the following blood tests:

What is the most likely diagnosis?

Select the SINGLE most appropriate option from the list below. Select ONE option only.