23rd May 2025

A 63-year-old female presents with symptomatic hypothyroidism which necessitates levothyroxine replacement long term.

A 63-year-old female presents with symptomatic hypothyroidism which necessitates levothyroxine replacement long term. She is known to have HTN and AF. She takes amlodipine 5 mg OD, apixaban  2.5mg BD and propranolol 10mg OD . What is the mechanism of interaction between levothyroxine and propranolol?

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