26th February 2025

A 63-year-old woman started chemotherapy two days ago for a diagnosis of metastatic small cell lung cancer

A 63-year-old woman started chemotherapy two days ago for a diagnosis of metastatic small cell lung cancer. She attends the A&E department complaining of breathlessness and headaches.

On examination, her observations are as follows: heart rate 118 bpm, blood pressure 136/68 mmHg, respiratory rate 24, oxygen saturation 96% on room air, temperature 36.8 degrees Celsius. You notice she has facial redness with some venous distension on her upper chest and neck. Her neurological examination is normal.

What is the most likely diagnosis?

Select the SINGLE most appropriate option from the list below. Select ONE option only.